Cross-sectional imaging in normal ageing
نویسندگان
چکیده
392 THE LANCET • Vol 363 • January 31, 2004 • www.thelancet.com Greater numbers of us are living longer than ever before. This increasing longevity will inevitably lead to a rise in the number of patients with degenerative dementias such as Alzheimer’s disease, the prevalence of which increases exponentially after the age of 65. In addition to devastating cognitive impairment, these disorders are characterised by early and accelerating cerebral atrophy. MRI could therefore be used to distinguish these conditions from normal ageing. Methodological advances in MRI now allow characterisation of the structural changes that accompany healthy brain ageing, and might help differentiate them from neurodegeneration.
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